Child: Care, Health and Development – Establishing a multidisciplinary specialist centre for fetal alcohol spectrum disorders—Lessons learned from a model project in Germany
Our service was used by both caregivers and professionals who reported numerous and complex concerns and needs. Professionally sound and multidisciplinary services are viable instruments to meet those needs, bearing the potential for quick and notable relief among individuals affected.
https://onlinelibrary.wiley.com/doi/10.1111/cch.13143
Res Dev Disabil – Prognostic factors for long-term outcome in children with fetal alcohol spectrum disorders. Even though our results need to be interpreted with caution due to methodological limitations such as the use of a convenience sample and limited statistical power, they imply that severely affected children with FASD experience a less stable environment.
https://pubmed.ncbi.nlm.nih.gov/36924617/
Applied Sciences – Assessment of the Central Nervous System in Children with Fetal Alcohol Spectrum Disorder (FASD) Using Magnetic Resonance (MR) Techniques. The analysis of the present findings in the study group showed that brain MRI examinations of children with FASD more often identified a decreased corpus callosum and 1H MRS and DWI abnormalities, particularly in the region of basal ganglia.
https://www.mdpi.com/2076-3417/13/12/7303
Biochimica et Biophysica Acta (BBA) – Molecular Basis of Disease – Neuroinflammation in fetal alcohol spectrum disorders and related novel therapeutic approaches. Despite evidence of its importance, neuroinflammation is not usually considered at diagnosis or treatment for FASD. Here, we discuss the literature regarding anti- inflammatory drugs and nutraceuticals, which hold promise for future therapeutical interventions in these disorders.
https://www.sciencedirect.com/science/article/abs/pii/S092544392300220X
BMC Proceedings – Fetal alcohol spectrum disorders prevention and clinical guidelines research-workshop report
It is estimated that up to 1 in 20 people in the United States are affected by fetal alcohol spectrum disorders (FASD), an array of cognitive, emotional, physical and social disorders caused by exposure to alcohol during prenatal development.
https://bmcproc.biomedcentral.com/articles/10.1186/s12919-023-00272-z
Alcohol – Proceedings of the 2022 Annual Meeting of the Fetal Alcohol Spectrum Disorders Study Group
The 2022 Fetal Alcohol Spectrum Disorders Study Group (FASDSG) meeting was held in coordination with the 45th annual Research Society on Alcoholism conference on June 25th, 2022.
https://www.sciencedirect.com/science/article/abs/pii/S0741832923002549
eClinicalMedicine – Parental substance use disorder and risk of intellectual disability in offspring in Sweden: a national register study. Both paternal and maternal SUD were associated with an increased risk of ID in offspring, with greatest risk observed when AUD was diagnosed during pregnancy.
https://www.sciencedirect.com/science/article/pii/S2589537023003474
International Indigenous Policy Journal – Client Perceptions of an FASD-Informed Indigenous Restorative Justice Program. Individuals with fetal alcohol spectrum disorder (FASD) can experience multiple layers of adversity that increase vulnerability to justice involvement.
https://ojs.lib.uwo.ca/index.php/iipj/article/view/14843
Alcohol: Clinical and Experimental Research – Prenatal alcohol exposure and cognition at midlife: Evidence of fluid cognition deficits in two cohorts. While all participants with PAE had lower fluid cognition, those with PAE and dysmorphic features also exhibited specific deficits in their performance on measures of inhibition, attention, and cognitive flexibility.
https://onlinelibrary.wiley.com/doi/abs/10.1111/acer.15177
Alcohol and Alcoholism – Pregnancy-specific alcohol policies and admissions to substance use disorder treatment for pregnant people in the USA. Pregnancy-specific alcohol policies related to greater treatment admissions tend to mandate treatment rather than make voluntary treatment more accessible, raising questions of ethics and effectiveness.
https://academic.oup.com/alcalc/advance-article-abstract/doi/10.1093/alcalc/agad056/7250138
BMC Medicine – Alcohol exposure before and during pregnancy is associated with reduced fetal growth: the Safe Passage Study
This study demonstrated that PAE negatively affects fetal growth, in particular when exposed during the periconception period or in second trimester.
https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-023-03020-4
BMC Pregnancy and Childbirth – Associations between prenatal alcohol and tobacco exposure on Doppler flow velocity waveforms in pregnancy: a South African study. In our study, PTE in trimesters two and three resulted in increased vascular resistance of the placenta. These findings highlight nuance in associations between PAE, PTE and blood flow velocities in arteries of the fetal-placental-maternal circulation and birth weight, suggesting that quantity and timing are important factors in these relationships.
https://bmcpregnancychildbirth.biomedcentral.com/articles/10.1186/s12884-023-05881-2
Western University – Offspring Susceptibility of Developing Depressive-like Phenotypes and Metabolic Dysfunction Following Prenatal Alcohol Exposure and Juvenile Stress in a Mouse Model
Prenatal alcohol exposure (PAE) is the leading preventable cause of adverse fetal outcomes. Individuals with PAE are susceptible to developing secondary deficits such as depression and metabolic disorders.
https://ir.lib.uwo.ca/etd/9457/
International Journal of Mental Health and Addiction – Relationship Between Criminal and Status Offense Behaviors, Substance Use, and HIV Risk Among Adolescent Girls and Young Women in Cape Town, South Africa. This study aimed to examine the relationship between externalizing behaviors, substance use, and sexual risk among adolescent girls and young women (AGYW) in Cape Town, South Africa, who experience social disadvantage characterized by poverty and school dropout.
https://link.springer.com/article/10.1007/s11469-023-01130-x
University of Exeter – Application of fish models for studying mechanisms of human fetal alcohol spectrum disorders (FASDs). In this project, embryos from two small fish species, zebrafish (freshwater) and Arabian killifish (AKF) (seawater and brackish water), have been used as suitable models to study the mechanism of human fetal alcohol spectrum disorders (FASDs).
https://ore.exeter.ac.uk/repository/handle/10871/133848
Aten Primaria – Considerations for the design and implementation of interventions for the cessation of tobacco, alcohol and cannabis use in pregnancy: A qualitative study. The conclusion is that this intervention should be carried out at the level of prenatal care in primary care. There are doubts regarding the frequency, purpose, and follow-up of this multicomponent intervention, as well as the possibility of incorporating couples.
https://pubmed.ncbi.nlm.nih.gov/37573833/
European Archives of Psychiatry and Clinical Neuroscience – Effects of prenatal alcohol exposition on cognitive outcomes in childhood and youth: a longitudinal analysis based on meconium ethyl glucuronide. Subclinical PAE, as determined by meconium EtG, has negative developmental consequences on cognitive function that persist from childhood to adolescence.
https://link.springer.com/article/10.1007/s00406-023-01657-z
American Journal of Obstetrics & Gynecology MFM – Clinician views on reporting pregnant and birthing patients who use alcohol and/or drugs to child welfare. Participants agreed with most, but not, all child welfare reporting decisions. When participants disagreed or felt conflicted with reporting decisions, these feelings were almost entirely related to decisions to report, which, in some cases, were prompted by hospital or state policies. https://www.sciencedirect.com/science/article/pii/S2589933323002513