Rffada acknowledges and thanks the work of EUFASD in sourcing and compiling international research.
Research
Alcohol – Single essential oils and their binary mixtures protect against ethanol-induced defects in a zebrafish fetal alcohol spectrum disorder model at the same level as folic acid
This study evaluated protective effects of clove (SEO), thyme white (TEO), oregano (OEO), and caraway (CEO) essential oils (EOs), and their binary mixtures, in a zebrafish fetal alcohol spectrum disorder model.
https://www.sciencedirect.com/science/article/abs/pii/S0741832924001757
Pedagogy in Health Promotion – Delivering Education Through a Podcast to Change Provider Practice: A Mixed Methods Evaluation of a Fetal Alcohol Spectrum Disorders Podcast
Education delivered through podcasts can be effective in improving provider knowledge and self-efficacy and in promoting practice change. Podcasts offer broad reach and accessibility providing an opportunity to educate on topics including FASD.
https://journals.sagepub.com/doi/abs/10.1177/23733799241298257
helda.helsinki.fi – Early environmental effects on the placental epigenome and gene expression, and newborns’ phenotype : Focusing on prenatal alcohol exposure and Assisted Reproductive Technology
To clarify the etiology of adverse health outcomes mediated by the prenatal environment, this thesis focused on two prevalent and socially significant, but rather distinct environmental factors, prenatal alcohol exposure (PAE) and assisted reproductive technology (ART).
https://helda.helsinki.fi/items/2e8ced58-aa0d-433f-b14f-01b0d4ed9c6d
Bratislavske lekarske listy – Risk factors for self-reported alcohol consumption during pregnancy
In accordance with certain European data, the best means of protection against alcohol consumption during pregnancy include complete abstinence prior to conception, pregnancy planning, and high-quality education regarding the negative effects of alcohol during pregnancy (Tab. 4, Ref. 19).
https://pubmed.ncbi.nlm.nih.gov/39487834/
Rivista do psichiatria – Italian Guidelines for the diagnosis and treatment of Fetal Alcohol Spectrum Disorders: structural abnormalities
Timely diagnosis and intervention are crucial as they can significantly enhance outcomes through appropriate support and management strategies. Increasing awareness among citizens about the detrimental effects of alcohol use disorders on newborn health is of utmost importance.
https://pubmed.ncbi.nlm.nih.gov/39470674/
Alcohol: Clinical and Experimental Research – Prenatal alcohol exposure and health at midlife: Self-reported health outcomes in two cohorts
Patients affected by alcohol may report greater frequency and range of health adversity. That PAE was only uniquely associated with a limited set of problems suggests that many health outcomes in midlife result from an initial vulnerability potentiated by postnatal stress resulting from other associated factors.
https://onlinelibrary.wiley.com/doi/abs/10.1111/acer.15441
IBRO Neuroscience Reports – Transgenerational of Oxidative Damage Induced by Prenatal Ethanol Exposure on Spatial Learning/Memory and BDNF in the of Male Rats
The findings underscore the role of OS in developmental and behavioral issues in FASD rat models and suggest that lasting transgenerational effects in the second generation may stem from alcohol-induced changes.
https://www.sciencedirect.com/science/article/pii/S2667242124000800
PrePrints – What Do We Know About Alcohol Consumption During Pregnancy and Foetal Alcohol Spectrum Disorder in Nigeria?
Despite limited empirical evidence, anecdotal reports suggest that alcohol consumption during pregnancy is not uncommon in Nigeria, driven by factors such as social norms, lack of awareness, and limited access to prenatal care and education.
https://www.preprints.org/manuscript/202410.1957
Alcohol, clinical & Experimental Research – Maternal alcohol consumption during pregnancy and child development: Role of ADH1B and ALDH2 gene polymorphisms-The Yamanashi Adjunct Study of the Japan Environment and Children’s Study
Our results suggest that alcohol consumption by pregnant females carrying the deficient variant ALDH2*2 genotype may increase the risk of developmental delay in their offspring.
https://pubmed.ncbi.nlm.nih.gov/39537314/
Archives of Women’s Mental Health – Severe alcohol withdrawal during pregnancy or early postpartum: maternal and fetal outcomes
The findings highlight the severe implications of AWS during pregnancy, impacting both maternal and fetal health. The severity of AWS requires attentive clinical management and preventative interventions.
https://link.springer.com/article/10.1007/s00737-024-01531-4
International Journal of Molecular Sciences – Prenatal Opioid and Alcohol Exposures: Association with Altered Placental Serotonin Transporter Structure and/or Expression
Fetal exposures to many drugs of abuse, e.g., opioids and alcohol (EtOH), are associated with adverse neurodevelopmental problems in early childhood, including abnormalities in activity of the serotonin (5HT) transporter (SERT), which transports 5HT across the placenta.
https://www.mdpi.com/1422-0067/25/21/11570
Authorea – Prenatal alcohol use or smoking and their effect on fetal growth, stratified by dose, timing and single or dual use: a prospective cohort study.
Dual exposure to smoking and drinking (even low) reduces fetal growth.
https://www.authorea.com/doi/full/10.22541/au.172983252.20277202
AIDS – Substance use during pregnancy and postpartum among individuals with perinatally-acquired HIV in the United States
Use of cannabis and alcohol were common during pregnancy and the first year postpartum among people with HIV in the United States (2007–2019), but there were no major differences in substance use during pregnancy based on mode of HIV acquisition.
https://journals.lww.com/aidsonline/abstract/2024/12010/substance_use_during_pregnancy_and_postpartum.17.aspx?context=latestarticles
International Journal of Law and Psychiatry – Fetal alcohol spectrum disorder (FASD) and the criminal justice system: A guide for legal professionals
This article is intended to provide valuable information and best practices for professionals in the legal system, particularly judges, prosecutors, defense attorneys, social workers/mitigation specialists, and psychologists, who are likely to encounter individuals living with FASD or suspected FASD early in the judicial process.
https://www.sciencedirect.com/science/article/abs/pii/S0160252724000785
BMC Medicine – Prenatal alcohol exposure and associations with physical size, dysmorphology and neurodevelopment: a systematic review and meta-analysis
This comprehensive review provides guidance on which components are most useful to consider in the diagnostic criteria for FASD.
https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-024-03656-w
International Social Work – Using living experience and practitioner research to create unique programmes providing help for caregivers, professionals and students to increase support for children living with Foetal Alcohol Spectrum Disorder
In this article, I draw on my intersectional identities as a caregiver of a child with Foetal Alcohol Spectrum Disorder, as a registered social worker with extensive experience in the justice sector, and as an employed educator and researcher at a tertiary institute, to explore how I have used these multiple identities to create new initiatives that support families where Foetal Alcohol Spectrum Disorder is an issue, and introduce critical disability training for professionals working in the field.
https://journals.sagepub.com/doi/full/10.1177/00208728241288018
Nutrients – Exploring Nutritional Status and Metabolic Imbalances in Children with FASD: A Cross-Sectional Study
These findings suggest that the principal issue among patients with FASD is an altered metabolism rather than nutritional deficiencies. Potential causes of these abnormalities could include oxidative stress and changes in body composition.
https://www.mdpi.com/2072-6643/16/19/3401
Military Medicine – Mapping the Fetal Alcohol Spectrum Disorder Continuum of Care Across the Military Health System
Findings suggest opportunities to raise awareness, educate providers, and improve guidelines, policies, and practices in the MHS.
https://academic.oup.com/milmed/advance-article/doi/10.1093/milmed/usae456/7811871
Journal of Public Child Welfare – Foster parents’ need for greater information sharing when caring for children with prenatal substance exposure within child welfare
This article presents information on how the child welfare (CW) system informs caregivers about prenatal substance exposure (PSE) and related concerns, and how those caregivers communicate back to CW about PSE issues.
https://www.tandfonline.com/doi/abs/10.1080/15548732.2024.2412672
CNS drugs – The Safety of Alcohol Pharmacotherapies in Pregnancy: A Scoping Review of Human and Animal Research
There is insufficient research on the safety of alcohol pharmacotherapies in pregnancy. Despite this, given alcohol’s teratogenic effects, naltrexone could be considered to help maintain abstinence in pregnant individuals with AUD, particularly when psychosocial treatments have failed.
https://link.springer.com/article/10.1007/s40263-024-01126-8
IJPDS – Identifying substance misuse related foetal anomaly cases in routinely collected data
A novel method to identify SM-related foetal anomaly cases using routinely collected data in Wales is provided. The published code to identify mothers and children exposed to SM-related events can also be reused in future projects.
https://ijpds.org/article/view/2789
Ultrasound in Obstetrics and Gynecology – Drinking even small amounts of alcohol during pregnancy could alter fetal brain structure
Alcohol consumption during pregnancy can affect fetal brain development, as seen in temporal brain asymmetry detected by fetal MRI.
https://obgyn.onlinelibrary.wiley.com/doi/full/10.1002/uog.27788
Journal of Applied Research in Intellectual Disabilities – Integrated service delivery for individuals with fetal alcohol spectrum disorder
This study may help to inform a roadmap for enhancing FASD service delivery and guiding FASD research and policy in Canada and beyond.
https://onlinelibrary.wiley.com/doi/full/10.1111/jar.13277
Multidisciplinary Reviews – A lifespan perspective on fetal alcohol syndrome: Developmental challenges and outcomes
This disorder represents the intersection of complicated societal, community, family, and biological circumstances that increase the risk for intergenerational suffering, health disparity, and social injustice.
https://malque.pub/ojs/index.php/mr/article/view/5512
Brain Communications – Subcortical volume in middle-aged adults with fetal alcohol spectrum disorders
Studies of youth and young adults with prenatal alcohol exposure (PAE) have most consistently reported reduced volumes of the corpus callosum, cerebellum and subcortical structures.
https://academic.oup.com/braincomms/article/6/5/fcae273/7748169
University of Guelph – Guilty Pleas in Youth and Young Adults with and without Fetal Alcohol Spectrum Disorder (FASD)
Overall, findings highlight the importance of developmentally-informed plea practices for youth, and suggest young adults may require more support throughout this process than previously thought.
https://atrium.lib.uoguelph.ca/items/3517fe89-b2ce-4f50-85e2-26ec35117a68
Disabilities and Autism: Ethics and Practice – Ethical Considerations Arising in the Assessment, Treatment, and Support of Individuals and Families Living with FASD
This chapter discusses the ethical challenges associated with crafting effective and non-stigmatizing public health messaging about FASD, issues of mother-blame and the villainizing of women who consume alcohol in pregnancy, and an overview of some of the ethical considerations in the assessment, diagnosis, treatment, and support of individuals and families living with FASD.
https://link.springer.com/chapter/10.1007/978-3-031-61565-8_30
Laurier – Exploring the Transition from Childhood to Adulthood for Adults with Fetal Alcohol Spectrum Disorder
Previous research has demonstrated that adults with fetal alcohol spectrum disorder (FASD) often lack support after reaching 18 years old because they are no longer eligible for the support they receive as children.
https://scholars.wlu.ca/etd/2692/
Western University – Improving the Educational Experience of Students with Fetal Alcohol Spectrum Disorder (FASD)
Fetal Alcohol Spectrum Disorder (FASD) is recognized as one of the leading causes of developmental disability in the Western world (Flannigan et al., 2018). Its prevalence is estimated at 4% of the population.
https://ir.lib.uwo.ca/oip/404/
Drug and Alcohol Dependence – Administratively reported fetal alcohol spectrum disorders in commercially- and Medicaid-insured samples of children in the United States, 2015 – 2021
Although an underestimate of the true population of children with FASDs, patterns in administratively reported FASDs by demographics were consistent with previous studies.
https://www.sciencedirect.com/science/article/abs/pii/S0376871624013450
Substance Use & Addiction Journal – Answering a Call to Action: Reducing Fetal Alcohol Spectrum Disorders Using a Healthcare Champion Model
Through the advocacy, education, and mission of these 6 health sectors in collaboration with national organizations and educational institutions, the evidence-based approach of alcohol SBI is being disseminated throughout the United States to reduce the harmful effects of prenatal alcohol exposure.
https://journals.sagepub.com/doi/abs/10.1177/29767342241271361
Paediatrics and Child Health – Drugs and alcohol in pregnancy: what a paediatrician needs to know, how to ask and why it matters
This article will explore the immediate and long-term impact of exposure to these substances in pregnancy and consider how to obtain an accurate history of exposure to drugs and alcohol in pregnancy as part of standard paediatric history taking.
https://www.sciencedirect.com/science/article/abs/pii/S1751722224001392
bioRxiv – Longitudinal mapping of cortical change during early adolescence associated with prenatal tobacco and/or alcohol exposure in the Adolescent Brain Cognitive DevelopmentSM Study
Cortical thickness (mm) and cortical surface area (mm2) measured approximately 2 years apart in early adolescence, across 68 bilateral cortical regions.
https://www.biorxiv.org/content/10.1101/2024.08.29.610335v1.abstract
Research – EUFASD 18 Aug 2024
These findings indicate that youth with FAS require urgent attention for each of the medically-related variables included in this study. The need for attention to their health care needs may increase as these youth transition from pediatric to adult health care services.
https://www.sciencedirect.com/
Health workers in this study requested high-quality training and the development of FASD practice guidelines to improve role clarity and clinical impact when working with FASD populations.
https://onlinelibrary.wiley.
Our findings indicate that the SACC population may be a valuable asset to identify novel disease-associated genetic loci for FASD and other diseases.
https://www.sciencedirect.com/
We conclude that the zebrafish model effectively mimics several FASD phenotypes observed in humans, confirming gene expression changes we have previously documented in a human observational study and providing a valuable platform for exploring the underlying mechanisms of alcohol-induced embryonic alterations and for developing diagnostic markers and therapeutic targets for early intervention.
https://www.biorxiv.org/
Children with FASDs combine significant vulnerabilities, associating exposure to alcohol during the preconception and/or the prenatal period, prematurity, complex familial and sociocultural living conditions, and a genetic anomaly in almost a quarter of cases.
https://www.mdpi.com/2227-
People with FASD have many strengths, which are often overlooked in research. They have been described as skilled musicians, artists and sportspeople with wide vocabularies who are resilient, compassionate, hardworking, and kind. Increasing attention is being paid to FASD but this is not enough.
https://osf.io/preprints/osf/
This study aimed to evaluate the knowledge and awareness of Occupational Therapists (OTs) in child development units about dangers of alcohol consumption during pregnancy and the characteristics of children with Fetal Alcohol Spectrum Disorder (FASD).
https://research.aota.org/
Together, these findings indicate that third trimester AE disrupts mPFC-HPC oscillatory interactions and choice behaviors.
https://www.biorxiv.org/
The survey provided a valuable snapshot of the local CLA population which will support the commissioning of services. It highlighted the need for ongoing data capture of health issues. A particular spotlight was thrown on the lack of easily available information on PAE and a consistent diagnostic and management pathway for FASD.
https://adc.bmj.com/content/
Research on FASD prevalence varies widely between countries, highlighting the need for country-specific data to inform effective alcohol legislation. In Canada, prevalence estimates are outdated, necessitating an update.
https://library-archives.
It is crucial to routinely screen childbearing-age and pregnant women for alcohol and other substance use as well as mental health problems in order to prevent adverse maternal and neonatal outcomes.
https://www.mdpi.com/2227-
Maximizing the use of technology, employing flexibility in program delivery, and institutionalizing processes and protocols improved workflow, efficiency, and program reach.
https://journals.sagepub.com/
Tobacco and alcohol are the two most common substances used during pregnancy, and both can disrupt neurodevelopment, resulting in cognitive and behavioural deficits including language difficulties. Previous studies show that children with prenatal substance exposure exhibit microstructural alterations in major white matter pathways, though few studies have investigated the impact of prenatal substance exposure on white matter microstructure and language skills during the toddler years.
https://www.frontiersin.org/
The results suggest that moderate prenatal alcohol exposure does not have a considerable effect on retention of spatial information, but produces a general reduction in anxiety-like behaviors in the elevated plus-maze.
https://www.sciencedirect.com/
Prenatal alcohol exposure (PAE) refers to the exposure of the developing fetus due to alcohol consumption during pregnancy and can have life-long consequences for learning, behavior, and health.
https://www.frontiersin.org/
Despite longstanding recommendations, screening and intervention practices for substance use appear inconsistent. With the recent emergence of vaping, no evidence of updated approaches to identifying e-cigarette consumption in pregnant women was found.
https://onlinelibrary.wiley.
PCE effects on adolescent alcohol sipping are indirect and are confounded with maternal behaviors before and during pregnancy.
https://osf.io/preprints/
Restrictions on grocery store spirits sales and BAC laws were associated with lower and higher alcohol treatment admission rates among pregnant people, respectively, suggesting general population alcohol policies are relevant for pregnant people’s treatment utilization.
https://www.jsad.com/doi/abs/
There is a need for system modifications to assess multiple behaviors simultaneously and alert providers when a combination of behaviors increases a specific health risk, such as an AEP.
https://journals.sagepub.com/
This review assesses both the international prevalence of PAU obtained using meconium biomarkers in general maternity populations and, when feasible, the level of agreement between meconium biomarkers and self-reported PAU.
https://onlinelibrary.wiley.
FASD remains considerably under-researched. While there has been an increase in the number of original FASD research articles published annually over time, this is much lower than expected compared to publication trends for other neurodevelopmental conditions, and the wider scientific literature.
https://pubmed.ncbi.nlm.nih.
This model provides new insights into the barriers and facilitators CAMHS clinicians experience when assessing and supporting CYP with probable or diagnosed FASD, highlighting key clinical implications.
https://pubmed.ncbi.nlm.nih.
Research – EUFASD News 11 Feb 2024
Advances in Pediatric Research – Washington and Alaska Statewide Fetal Alcohol Spectrum Disorder Diagnostic Clinical Networks: Comparison of Three Decades of 4-Digit Code
26 Nov 2023
Windsor Yearbook of Access to Justice – Bound by Blame: Sentencing, Colonialism, and Fetal Alcohol Spectrum DisorderGladue and Ipeelee send important messages to
12 Nov 2023
Gladue and Ipeelee send important messages to judges, but messages that have tensions within them that reflect the broader tensions of using
23 Oct 2023
Journal of Language and Communication Disorders – Comparing narrative storytelling ability in individuals with autism and fetal alcohol spectrum disordersWhile many aspects of
8 Nov 2023
Human brain mapping – Examining the effects of prenatal alcohol exposure on performance of the sustained attention to response task in children with
14 August 2023
Europe PMC – Protecting the future child: Foetal alcohol spectrum disorder, easy rescue and the regulation of maternal behaviourThis paper argues that social